Sleep restriction therapy -- systematically restricting and regularizing time in bed to stabilize sleep -- conducted by a nurse in a primary care setting reduced insomnia symptoms compared with sleep hygiene alone, according to the randomized HABIT trial.
At 6 months, the mean score on the Insomnia Severity Index (ISI) was 10.9 among participants who received nurse-delivered sleep restriction therapy versus 13.9 for those who received a sleep hygiene booklet only (P<0.0001), reported Simon Kyle, PhD, of the Sleep and Circadian Neuroscience Institute at the University of Oxford in England,
Mean adjusted differences in ISI -- which ranges from 0 to 28, with higher scores indicating more severe symptoms -- also significantly favored the intervention at both 3 and 12 months as well:
- 3 months: -3.88 (95% CI -4.66 to -3.10, P<0.0001)
- 12 months: -2.96 (95% CI -3.75 to -2.16, P<0.0001)
In addition, the incremental cost per quality-adjusted life-year (QALY) gained was £2,076 ($2638) with sleep restriction therapy, suggesting that the treatment had a 95.3% probability of being cost-effective based on a £20,000 ($25,412) cost-effectiveness threshold, Kyle and team said.
"Insomnia is a serious condition because it's highly prevalent, has a major effect on quality of life, and increases risk for developing other physical and mental health problems," Kyle said in a statementopens in a new tab or window. "The key issue is that people with chronic insomnia rarely receive evidence-based treatment."
Guidelines suggest that first-line treatment for insomnia should be multi-component cognitive behavioral therapy, "but access is extremely limited worldwide because of inadequate resources and expertise," the authors noted, with patients instead often prescribed hypnotic medication or off-label sedative antidepressants.
Sleep restriction therapy is a principal component of cognitive behavioral therapy, which "counters behaviors that perpetuate insomnia, specifically time-in-bed extension, variability in sleep-wake timing, and daytime napping," Kyle and team explained.
This brief nurse-delivered therapy can be both effective in treating insomnia disorder and improving certain aspects of mental health and functioning for these patients, they pointed out, adding that their study results could have implications for clinical practice in primary care settings because it is cost-effective without major increases in demands on nursing time.
"Future research is needed to understand how the nurse-delivered program could be implemented in the NHS, for example as part of a stepped care approach to insomnia management, and whether this may lead to reduction in prescriptions for sleep medication," Kyle said.
In an accompanying commentaryopens in a new tab or window, Annemieke van Straten, PhD, of Vrije Universiteit Amsterdam in the Netherlands, and co-authors, agreed that this approach could become an important therapy option for patients with insomnia.
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